Abstract | OBJECTIVE: METHOD: The risk of occurrence of complications associated with the use of these two rinsing and preserving solutions was estimated from a survey of 106 patients undergoing renal transplantation between 1 January 1993 and 31 March 1998. Both efficacy and adverse outcomes were recorded along with the costs directly associated with the transplantation procedure in the hospital setting: hospitalization, rinsing and preserving solutions, medical and technical interventions and diagnostic tests. RESULTS: For the 45 kidney grafts rinsed and preserved with Eurocollins (strategy S1: n1 = 45) the cost/graft was estimated at 40 euros. With Viaspan (strategy S2: n2 = 61) the corresponding cost/graft was 424 euros. Logistic regression analysis showed that Viaspan was better than Eurocollins solution (ebeta = 0.437; P = 0.05) in preventing DGF. Overall, S2 was less expensive than S1, from the hospital's perspective. The mean difference per patient was 278 euros, which amounts to a saving of 2% of the total cost per renal transplantation. For rinsing and preserving kidney grafts Belzer solution is therefore preferable to Eurocollins solution.
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Authors | J Vincentelli, A Luccioni, B Devictor, B Dussol, E Lechevallier, P Bertault-Peres, C Coulange, Y Berland, C Penot Ragon |
Journal | Journal of clinical pharmacy and therapeutics
(J Clin Pharm Ther)
Vol. 28
Issue 4
Pg. 273-7
(Aug 2003)
ISSN: 0269-4727 [Print] England |
PMID | 12911678
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
- Euro-Collins' solution
- Hypertonic Solutions
- Insulin
- Organ Preservation Solutions
- University of Wisconsin-lactobionate solution
- Allopurinol
- Glutathione
- Adenosine
- Raffinose
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Topics |
- Adenosine
(adverse effects, economics)
- Allopurinol
(adverse effects, economics)
- Cost Savings
- Cost-Benefit Analysis
- Glutathione
(adverse effects, economics)
- Graft Survival
- Humans
- Hypertonic Solutions
(adverse effects, economics)
- Insulin
(adverse effects, economics)
- Kidney
- Kidney Transplantation
(adverse effects, economics)
- Kidney Tubular Necrosis, Acute
(etiology, prevention & control)
- Organ Preservation
(methods)
- Organ Preservation Solutions
(adverse effects, economics)
- Raffinose
(adverse effects, economics)
- Retrospective Studies
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