Abstract |
Cefprozil (CFPZ, BMY-28100) granules were administered to 20 children with bacterial infections: acute tonsillitis 8, acute bronchitis 10, purulent lymphadenitis 1, urinary tract infection 1. Daily doses ranged 29-50 mg/kg. The drug was given orally, 3 times a day and the durations of administration were 5 to 9 days. Clinical efficacies were excellent in 16 cases and good in 4 cases, hence the overall efficacy rate was 100%. No side effects were observed in any of these cases. As for abnormal laboratory test values, thrombocytosis was observed in 1 case. From the above results, we consider CFPZ granules to be a useful drug for the treatment of pediatric patients with various bacterial infections.
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Authors | S Furukawa, T Okada |
Journal | The Japanese journal of antibiotics
(Jpn J Antibiot)
Vol. 45
Issue 12
Pg. 1658-62
(Dec 1992)
ISSN: 0368-2781 [Print] Japan |
PMID | 1289584
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Administration, Oral
- Age Factors
- Bacteria
(isolation & purification)
- Bacterial Infections
(drug therapy, microbiology)
- Cephalosporins
(administration & dosage, adverse effects, therapeutic use)
- Child
- Child, Preschool
- Drug Evaluation
- Female
- Humans
- Infant
- Male
- Thrombocytosis
(chemically induced)
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