[Lactose tolerance in children with chronic gastroduodenal zone diseases].

Abstract

We determined the dependence of the frequency of lactose intolerance, particular features of the clinical presentation and laboratory showings on lactase deficiency on the basis of a complex clinical, anamnestic and laboratory study of 149 children with chronic gastroduodenal pathologies. It was established that the prevalence of lactose intolerance in children with superficial gastroduodenitis amounts to 58.8%, in children with erosive gastroduodenitis--66.7% and in children with stomach ulcers--83.3%. During the oral lactose load and a subsequent laboratory study we revealed an impairment of the hydrolytic function of small intestines accompanied by an increase of fecal excretion of carbohydrates (lactose and monosaccharides) as well as a considerable enhancement of bacterial fermentation. The detection of fecal excretion of the total glycoprotein hexoses characterizes a disorder of the morphofunctional state of the gastrointestinal tract in children with intestinal enzymopathies.

• Authors: L Ia Klimov
• Journal: Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology (Eksp Klin Gastroenterol) Issue 2 Pg. 99-104, 120 ( 2003) ISSN: 1682-8658 [Print] Russia (Federation)
• Vernacular Title: Tolerantnost' k laktoze deteĭ s khronicheskimi zabolevaniiami gastroduodenal'noĭ zony.
• PMID: 12875008 (Publication Type: English Abstract, Journal Article)

Chemical References

• Lactose

Topics

• Adaptation, Physiological
• Adolescent
• Child
• Duodenal Diseases (physiopathology)
• Female
• Humans
• Lactose (administration & dosage)
• Lactose Intolerance (physiopathology)
• Male
• Stomach Diseases (physiopathology)