Abstract | OBJECTIVE: DESIGN: Cohort of patients with a median follow-up of 46 months (range, 1-174 months). SETTING: University-based referral center. PATIENTS: A total of 160 consecutive patients with complete clinical and pathologic data. INTERVENTION: MAIN OUTCOME MEASURE: Incidence of apparent and occult lymph node metastases. Univariate and multivariate analyses were used to evaluate the significance of clinical and pathologic data. RESULTS: Histologically confirmed positive neck was found in 53% of all cases. Histologic diagnosis was significantly related to the incidence of lymph node metastasis: 89% (16/18) for undifferentiated carcinomas. However, so-called low-risk tumors had incidence rates of 22% to 47%. Twenty-one patients (13%) presented with clinically apparent cervical lymph node metastasis. Of the 139 patients with clinical N0 neck, 45% had occult neck metastasis. Neck metastasis was found in 29% (10/34) of T1, 54% (38/70) of T2, 65% (20/31) of T3, and 54% (16/25) of T4 tumors. Assessment of survival according to nodal status revealed significant correlations for overall (P<.001) and disease-free survival (P<.001). CONCLUSIONS:
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Authors | Eberhard Stennert, Dilek Kisner, Markus Jungehuelsing, Orlando Guntinas-Lichius, Ursula Schröder, Hans Edmund Eckel, Jens Peter Klussmann |
Journal | Archives of otolaryngology--head & neck surgery
(Arch Otolaryngol Head Neck Surg)
Vol. 129
Issue 7
Pg. 720-3
(Jul 2003)
ISSN: 0886-4470 [Print] United States |
PMID | 12874071
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Adenocarcinoma
(pathology)
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Carcinoma, Squamous Cell
(pathology)
- Child
- Disease-Free Survival
- Female
- Humans
- Lymph Node Excision
- Lymphatic Metastasis
- Male
- Middle Aged
- Neoplasm Staging
- Retrospective Studies
- Risk Factors
- Salivary Gland Neoplasms
(mortality, pathology)
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