[Slow ventricular tachycardia caused by naftidrofuryl overdose (naftidrofuryl and ventricular tachycardia)].

Abstract

Treatment with intravenous naftidrofuryl may be complicated by ventricular arrhythmias. A case of slow ventricular tachycardia occurring in a 65-year-old man with a dilated cardiomyopathy following an accidental overdose of naftidrofuryl (2 x 200 mg ampules in 250 ml of 5% glucose solution in 2 hours) prescribed for complicated arterial disease of the lower limbs is reported. This sustained ventricular tachycardia converted spontaneously after several hours. This case emphasises the risk of arrhythmogenic effects of this drug and indicates the need for careful monitoring when it is used intravenously in patients with underlying heart disease.

• Authors: H R Malaterre, A Ferracci, A Ebagosti, J P Faugier, D Charles, S Levy
• Journal: Annales de cardiologie et d'angeiologie (Ann Cardiol Angeiol (Paris)) Vol. 41 Issue 7 Pg. 379-81 (Sep 1992) ISSN: 0003-3928 [Print] France
• Vernacular Title: Tachycardie ventriculaire lente par surdosage en naftidrofuryl (naftidrofuryl et TV).
• PMID: 1285624 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Nafronyl

Topics

• Aged
• Cardiomyopathy, Dilated (drug therapy)
• Drug Overdose
• Humans
• Iatrogenic Disease
• Male
• Nafronyl (administration & dosage, adverse effects)
• Tachycardia, Ventricular (chemically induced)