[An open non-comparative study of impase for treating erectile dysfunction].
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| Abstract |
Clinical efficacy and safety of the drug impase in erectile dysfunction (ED) were studied in 30 patients with ED of various genesis (mean age 52.09 +/- 4.75 years). IIED questionnairing was employed, combined andrological examination and standard laboratory investigations. Impase was taken 1 tablet a day each other day for 12 weeks irrespective of the intercourse. The number of attempted intercourses was at least 4 times a month. The treatment efficacy was assessed by changes of IIED parameters, subjective and objective effects. ED was psychogenic in 5 (16.7%) patients, organic in 25 (83.3%) patients. Blood hormones were normal for age in all the patients. According to IIED, "erectile function" mean score after 12 week treatment rose from 18.89 +/- 5.25 to 22.50 +/- 4.86. In 11 (36.7%), 4 (13.3%), 5 (16.7%) patients the response was rated as excellent, good and satisfactory, respectively. No response was stated in 10 (33.3%) patients. Side effects were absent. Tolerance and safety were excellent. Thus, efficacy of impase therapy varied from 60 to 66.7% depending on ED etiology and pathogenesis. Cost-efficacy, absence of side effects, possible parallel therapy of concurrent diseases, course administration are advantages of the treatment.
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| Authors | E B Mazo, S I Gamidov, R I Ovchinnikov |
| Journal | Urologiia (Moscow, Russia : 1999) (Urologiia) 2003 May-Jun Issue 3 Pg. 28-31 ISSN: 1728-2985 [Print] Russia (Federation) |
| Vernacular Title | Otkrytoe nespravnitel'noe issledovanie preparata impazy dliia lecheniia érektil'noĭ disfinktsii. |
| PMID | 12846094 (Publication Type: Clinical Trial, English Abstract, Journal Article) |
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