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Cystic fibrosis: premature degradation of mutant proteins as a molecular disease mechanism.

AuthorsMarina S Gelman, Ron R Kopito
JournalMethods in molecular biology (Clifton, N.J.) (Methods Mol Biol) Vol. 232 Pg. 27-37 ( 2003) ISSN: 1064-3745 [Print] United States
PMID12840537 (Publication Type: Journal Article, Review)
Chemical References
  • CFTR protein, human
  • Multienzyme Complexes
  • Ubiquitin
  • cystic fibrosis transmembrane conductance regulator delta F508
  • Cystic Fibrosis Transmembrane Conductance Regulator
  • Cysteine Endopeptidases
  • Proteasome Endopeptidase Complex
Topics
  • Cysteine Endopeptidases (metabolism)
  • Cystic Fibrosis (genetics, metabolism, therapy)
  • Cystic Fibrosis Transmembrane Conductance Regulator (genetics, metabolism)
  • Humans
  • Multienzyme Complexes (metabolism)
  • Mutation
  • Proteasome Endopeptidase Complex
  • Protein Folding
  • Ubiquitin (metabolism)

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