Abstract | OBJECTIVE: To reveal the role of HPV in the occurrence and development of cholesteatoma of the middle ear. METHOD: RESULTS: Pathologically, the characteristics of HPV induced-lesions was found in 12 of 35 specimens (34.3%). 44 cases of middle ear cholesteatoma were examined with consensus primers PCR and digoxigenin labeled HPV general probes. HPV DNA positive rates were 29.5% (13/44) and 25.0% (11/44) respectively. HPV DNA positive rate was 58.3% (7/12) and 13.0% (3/23) respectively in 12 cases with pathological characteristics of HPV induced-lesions and in 23 cases without those characteristics. There was significant difference(chi 2 = 7.926, P < 0.005). CONCLUSIONS:
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Authors | Y Bai, L Yan, S Li, Q Bai |
Journal | Zhonghua er bi yan hou ke za zhi
(Zhonghua Er Bi Yan Hou Ke Za Zhi)
Vol. 35
Issue 5
Pg. 352-5
(Oct 2000)
ISSN: 0412-3948 [Print] China |
PMID | 12768735
(Publication Type: English Abstract, Journal Article)
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Chemical References |
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Topics |
- Adolescent
- Adult
- Child
- Cholesteatoma, Middle Ear
(pathology, virology)
- DNA, Viral
(analysis)
- Humans
- Middle Aged
- Papillomaviridae
(genetics)
- Papillomavirus Infections
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