A serological survey of arboviral diseases among the human population of the Andaman and Nicobar Islands, India.

Abstract	In an attempt to determine the prevalence of certain arthropod-borne viruses of public health importance amongst the human population of the Andaman and Nicobar Islands of India, 2,401 sera were collected from six major localities. The sera were analysed by the hemagglutination inhibition (HI) and neutralization (N) tests, using Chikungunya (CHIK), Japanese encephalitis (JE), West Nile (WN), dengue (DEN-2), Langat (TP-21) and Kyasanur Forest disease (KFD) viral antigens. The highest prevalence of HI antibodies was detected against KFD virus (22.4%), followed by Langat (20.2%), JE (5.9%), DEN-2 (3.1%), CHIK (2.9%) and WN (0.8%) viruses. Cross-reactions to the viral antigens were also noted. The results of N tests indicated a high prevalence of DEN-2 (25.4%) virus, followed by Langat (17.5%), CHIK (15.3%), KFD (12%), JE (2.19%) and WN (1.8%). These results are discussed in relation to important epidemiological parameters like age, sex and geographical location. To our knowledge, this is the first report of an extensive serosurvey of arthropod-borne viruses on these islands.
Authors	V S Padbidri, N S Wairagkar, G D Joshi, U B Umarani, A R Risbud, D L Gaikwad, S S Bedekar, A D Divekar, F M Rodrigues
Journal	The Southeast Asian journal of tropical medicine and public health (Southeast Asian J Trop Med Public Health) Vol. 33 Issue 4 Pg. 794-800 (Dec 2002) ISSN: 0125-1562 [Print] Thailand
PMID	12757228 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References	Antibodies, Viral
Topics	Adolescent Adult Age Distribution Antibodies, Viral (blood) Arbovirus Infections (blood, diagnosis, epidemiology, immunology, virology) Chikungunya virus (immunology) Child Child, Preschool Dengue Virus (immunology) Encephalitis Virus, Japanese (immunology) Encephalitis Viruses, Tick-Borne (immunology) Female Hemagglutination Inhibition Tests Humans India (epidemiology) Infant Male Neutralization Tests Population Surveillance Residence Characteristics Seroepidemiologic Studies Sex Distribution West Nile virus (immunology)

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