Abstract | BACKGROUND: METHODS:
PONV and pain were evaluated in 29 boys during the first 24 h after daycase penile surgery. Anaesthesia was standardized. The patients were allocated to two groups. Fentanyl 1 micro g.kg-1 i.v. or placebo was administered in a randomized, double-blind design. A caudal block with ropivacaine 2 mg.ml-1, 0.5 ml.kg-1 was performed preoperatively and topical lidocaine gel 20 mg.ml-1 was applied over the wound area immediately after surgery. RESULTS: The total incidence of PONV in hospital and at home during the first 24 h was 36% (5/14) when fentanyl was used, whereas no PONV was reported when placebo was given (P < 0.05). The median time to first administration of analgesics after the caudal block was approximately 6 h. It did not differ between groups. Intraoperative fentanyl did not result in any reduction in pain scores nor the incidence of pain. Fentanyl caused apnoea in one-half of the cases and decreased the breathing rates during the first 10 min of surgery. CONCLUSIONS: Intraoperative use of i.v. fentanyl 1 micro g.kg-1 combined with a regional anaesthetic block is associated with an increased incidence of PONV without any significant contribution to the postoperative pain relief.
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Authors | E Kokinsky, K Nilsson, L E Larsson |
Journal | Paediatric anaesthesia
(Paediatr Anaesth)
Vol. 13
Issue 4
Pg. 334-8
(May 2003)
ISSN: 1155-5645 [Print] France |
PMID | 12753447
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
- Anesthetics, Combined
- Anesthetics, Intravenous
- Fentanyl
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Topics |
- Adolescent
- Ambulatory Surgical Procedures
- Anesthesia, Caudal
- Anesthetics, Combined
(adverse effects)
- Anesthetics, Intravenous
(administration & dosage, adverse effects)
- Child
- Child, Preschool
- Dose-Response Relationship, Drug
- Double-Blind Method
- Fentanyl
(administration & dosage, adverse effects)
- Humans
- Male
- Pain, Postoperative
(prevention & control)
- Penis
(surgery)
- Postoperative Nausea and Vomiting
(etiology)
- Respiration
(drug effects)
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