Abstract | BACKGROUND:
Syringoma of the vulva has been rarely reported. No effective treatment modality has been documented. OBJECTIVE: The purpose of this study was to describe the clinicopathologic features of vulvar syringoma, to investigate the hormonal influence on its growth, and to establish an effective treatment modality. METHODS: RESULTS: The age of first presentation at our vulvar clinic ranged from 21 to 60 years with a median age of 29.5 years. Of patients, 13 (72%) had vulvar pruritus and 7 noticed aggravation during summer or during menstruation. The most common clinical appearance was multiple flesh-colored or brownish papules on bilateral sides of the vulva (9 of 18). One third of our series was found to have coexisting eyelid syringoma and 4 of them also had a family history of periorbital syringoma. Immunohistochemical stainings for estrogen receptor and progesterone receptor were all negative on the 15 cases studied. Of our patients, 7 with intense pruritus were treated with carbon dioxide laser vaporization. Their lesions resolved and pruritus subsided. CONCLUSION:
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Authors | Yu-Huei Huang, Ya-Hui Chuang, Tseng-tong Kuo, Li-Cheng Yang, Hong-Shang Hong |
Journal | Journal of the American Academy of Dermatology
(J Am Acad Dermatol)
Vol. 48
Issue 5
Pg. 735-9
(May 2003)
ISSN: 0190-9622 [Print] United States |
PMID | 12734503
(Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Adult
- Carbon Dioxide
(therapeutic use)
- Diagnosis, Differential
- Female
- Humans
- Immunohistochemistry
- Laser Therapy
- Middle Aged
- Prognosis
- Pruritus
(etiology, pathology)
- Sweat Gland Neoplasms
(immunology, pathology, surgery)
- Syringoma
(immunology, pathology, surgery)
- Treatment Outcome
- Vulvar Diseases
(diagnosis)
- Vulvar Neoplasms
(immunology, pathology, surgery)
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