Abstract | INTRODUCTION: METHODS: RESULTS: Increasing age and postmenopausal status were associated with more advanced manifestations of steroid-induced osteoporosis (p < 0.05). One year after the start of therapy parameters of bone metabolism increased significantly in group 1, while BMD did not change. In group 2, lumbar spine BMD increased significantly (p < 0.05) whereas femoral neck BMD and bone metabolism parameters remained constant. The intensity of back pain decreased in both groups (p < 0.05). There were fewer new fractures in group 2 than in group 1. CONCLUSION:
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Authors | K Loddenkemper, A Grauer, G R Burmester, F Buttgereit |
Journal | Clinical and experimental rheumatology
(Clin Exp Rheumatol)
2003 Jan-Feb
Vol. 21
Issue 1
Pg. 19-26
ISSN: 0392-856X [Print] Italy |
PMID | 12673885
(Publication Type: Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Glucocorticoids
- Vitamin D
- Prednisolone
- Etidronic Acid
- Calcium
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Back Pain
(drug therapy, physiopathology, prevention & control)
- Bone Density
(drug effects)
- Calcium
(therapeutic use)
- Etidronic Acid
(therapeutic use)
- Female
- Femur Neck
(drug effects, metabolism)
- Fractures, Spontaneous
(prevention & control)
- Glucocorticoids
(adverse effects)
- Humans
- Lumbar Vertebrae
(drug effects, metabolism)
- Male
- Middle Aged
- Osteoporosis
(chemically induced, drug therapy, prevention & control)
- Prednisolone
(adverse effects)
- Prospective Studies
- Rheumatic Diseases
(drug therapy)
- Treatment Outcome
- Vitamin D
(therapeutic use)
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