Abstract | BACKGROUND: METHODS: A randomized placebo-controlled clinical trial was used to test IEVI that engaged patients in infection and depression prevention and problem-solving activities with professionals. The primary outcome measure was CR-BSIs, while reactive depression and problem solving were secondary outcomes. Quality of life and satisfaction with interventions, also secondary outcomes, were evaluated at 18 months. RESULTS: Compared with controls, there was a lower frequency in the experimental group of CRBSIs (chi2 = 4.82, p = .03), reactive depression (chi2 = 4.50, p = .03), and rehospitalization for CR-BSIs (chi2 = 5.73, p = .01). There was greater use of problem solving in the experimental group (chi2 = 4.33, p = .038). These differences occurred at the primary endpoint of 6 months after administration of the interventions. At the 18-month follow-up, there were fewer CR-BSIs (chi2 = 4.42, p = .035), and fewer hospitalizations for infection (chi2 = 5.729, p = .01). CONCLUSIONS: The IEVI reduced CR-BSIs and reactive depression and increased problem solving with professionals. IEVI use also can result in fewer hospitalizations and improved quality of life. Long-term improvement did not occur for reactive depression and problem-solving outcomes because patients used these less often.
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Authors | Carol E Smith, Susan Curtas, Susan V M Kleinbeck, Marilyn Werkowitch, Michael Mosier, Douglas L Seidner, Ezra Steiger |
Journal | JPEN. Journal of parenteral and enteral nutrition
(JPEN J Parenter Enteral Nutr)
2003 Mar-Apr
Vol. 27
Issue 2
Pg. 137-45
ISSN: 0148-6071 [Print] United States |
PMID | 12665170
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, U.S. Gov't, P.H.S.)
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Topics |
- Adolescent
- Adult
- Catheters, Indwelling
(adverse effects, microbiology)
- Depression
(etiology, prevention & control)
- Equipment Contamination
(prevention & control)
- Female
- Hospitalization
- Humans
- Infection Control
- Male
- Middle Aged
- Parenteral Nutrition, Home
(adverse effects)
- Patient Education as Topic
(methods)
- Problem Solving
- Quality of Life
- Sepsis
(etiology, prevention & control)
- Treatment Outcome
- Videotape Recording
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