[Cerebrospinal fluid phospholipids and cerebrosides in several demyelinating diseases].

Abstract

The author reports of the achieved results in a quantitative study of general lipids, phospholipids and cerebrosides in the CSF of 37 patients with demyelinating diseases, of 11 patients with vascular brain pathology and 7 with Van Bogart's panencephalitis. The control group consisted of 14 patients without focal lesions of the nervous system, with normal CSF indices. In demyelinating diseases there was a significant increase in the content of kephalines and cerebrosides. In Van Bogart's panencephalitis there was a much higher increase of kephalines, general lipids and phospholipids. In vascular brain disorders there was a moderate increase of all lipids. The possible pathochemical mechanisms of the depicted changes in the content of the lipids in the CSF are discussed.

• Authors: N A Drobysheva
• Journal: Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952) (Zh Nevropatol Psikhiatr Im S S Korsakova) Vol. 76 Issue 2 Pg. 218-24 ( 1976) ISSN: 0044-4588 [Print] Russia (Federation)
• Vernacular Title: Fosfolipidy i tserebrozidy likvora pri nekotorykh demieliniziruiushchikh zabolevaniiakh
• PMID: 1266483 (Publication Type: English Abstract, Journal Article)

Chemical References

• Cerebrosides
• Cerebrospinal Fluid Proteins
• Lipids
• Phosphatidylethanolamines
• Phospholipids

Topics

• Adolescent
• Adult
• Cerebrosides (cerebrospinal fluid)
• Cerebrospinal Fluid Proteins (cerebrospinal fluid)
• Cerebrovascular Disorders (cerebrospinal fluid)
• Demyelinating Diseases (cerebrospinal fluid)
• Diffuse Cerebral Sclerosis of Schilder (cerebrospinal fluid)
• Female
• Humans
• Lipids (cerebrospinal fluid)
• Male
• Middle Aged
• Multiple Sclerosis (cerebrospinal fluid)
• Phosphatidylethanolamines (cerebrospinal fluid)
• Phospholipids (cerebrospinal fluid)
• Subacute Sclerosing Panencephalitis (cerebrospinal fluid)