Mediterranean spotted fever during pregnancy: case presentation and literature review.

Abstract

Mediterranean spotted fever (MSF) is caused by Rickettsia conorii, an obligate intracellular parasite of eukaryotic cells. Although, usually this disease has a benign course, a rapidly fatal outcome can occur even in young healthy adults. We describe a case of a 40-year-old Bedouin woman gravida 11, para 10, who was admitted at 36 weeks gestation with this rickettsial disease. During pregnancy, the treatment of choice for Mediterranean spotted fever is chloramphenicol, but it seems that Azithromycin could be another possible option.

• Authors: Yaakov Bentov, Eyal Sheiner, Shlomit Kenigsberg, Moshe Mazor
• Journal: European journal of obstetrics, gynecology, and reproductive biology (Eur J Obstet Gynecol Reprod Biol) Vol. 107 Issue 2 Pg. 214-6 (Apr 25 2003) ISSN: 0301-2115 [Print] Ireland
• PMID: 12648874 (Publication Type: Case Reports, Journal Article, Review)
• Copyright: Copyright 2002 Elsevier Science Ireland Ltd.

Chemical References

• Anti-Bacterial Agents
• Antibodies, Bacterial
• Immunoglobulin G
• Immunoglobulin M
• Chloramphenicol
• Cefuroxime

Topics

• Adult
• Anti-Bacterial Agents (therapeutic use)
• Antibodies, Bacterial (blood)
• Arabs
• Boutonneuse Fever (diagnosis, drug therapy)
• Cefuroxime (therapeutic use)
• Chloramphenicol (therapeutic use)
• Female
• Gestational Age
• Humans
• Immunoglobulin G (blood)
• Immunoglobulin M (blood)
• Infant, Newborn
• Israel
• Male
• Pregnancy
• Pregnancy Complications, Infectious (diagnosis)
• Rickettsia conorii (immunology)