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Autoantibody in mucous membrane pemphigoid binds to an intracellular epitope on human beta4 integrin and causes basement membrane zone separation in oral mucosa in an organ culture model.

AuthorsK C Bhol, J E Colon, A R Ahmed
JournalThe Journal of investigative dermatology (J Invest Dermatol) Vol. 120 Issue 4 Pg. 701-2 (Apr 2003) ISSN: 0022-202X [Print] United States
PMID12648237 (Publication Type: Letter, Research Support, U.S. Gov't, P.H.S.)
Chemical References
  • Autoantibodies
  • Epitopes
  • Integrin beta4
Topics
  • Animals
  • Autoantibodies (immunology, metabolism)
  • Basement Membrane (immunology)
  • Epitopes (immunology, metabolism)
  • Humans
  • Integrin beta4 (immunology, metabolism)
  • Mouth Mucosa (immunology)
  • Organ Culture Techniques
  • Pemphigoid, Benign Mucous Membrane (immunology)

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