Abstract |
We evaluated program entry, retention, and early treatment response of needle exchange program (NEP) attenders referred to a drug treatment program using levomethadyl acetate hydrochloride ( LAAM). Of 163 referrals, 114 (70%) entered the program, and 84% were retained for at least 90 days. Comparing baseline and follow-up visits after 1 month, there were significant reductions in the Addiction Severity Index subscale scores for drug and alcohol use and legal situation. We observed a 31% and 22% reduction in heroin- and cocaine-positive urine tests, respectively (p < .0001). Although LAAM is no longer considered a first line treatment for heroin addiction, these results demonstrate the feasibility of utilizing long-acting agonist therapies such as LAAM to treat opioid dependence among NEP attenders.
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Authors | Irene Kuo, Joseph Brady, Carol Butler, Robert Schwartz, Robert Brooner, David Vlahov, Steffanie A Strathdee |
Journal | Journal of substance abuse treatment
(J Subst Abuse Treat)
Vol. 24
Issue 1
Pg. 67-74
(Jan 2003)
ISSN: 0740-5472 [Print] United States |
PMID | 12646332
(Publication Type: Comparative Study, Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, U.S. Gov't, P.H.S.)
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Copyright | Copyright 2003 Elsevier Science Inc. |
Chemical References |
- Narcotics
- Methadyl Acetate
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Topics |
- Adult
- Baltimore
(epidemiology)
- Cocaine-Related Disorders
(epidemiology, therapy, urine)
- Feasibility Studies
- Female
- Heroin Dependence
(epidemiology, therapy, urine)
- Humans
- Male
- Methadyl Acetate
(administration & dosage, therapeutic use)
- Mobile Health Units
- Narcotics
(administration & dosage, therapeutic use)
- Needle-Exchange Programs
- Referral and Consultation
- Severity of Illness Index
- Substance Abuse Treatment Centers
(organization & administration)
- Substance-Related Disorders
(epidemiology, therapy, urine)
- Time Factors
- Treatment Outcome
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