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Löffler's endocarditis associated with unusual ECG change mimicking posterior myocardial infarction.

Abstract
A73-year-old man with a history of bronchial asthma and atrial fibrillation was admitted to our hospital because of dyspnea and back pain. Blood analysis revealed a marked increase in total blood cell and eosinophil counts. The creatine kinase and creatine kinase-MB increased slightly. The ECG demonstrated significant ST-segment depression that mimicked acute posterior myocardial infarction. Emergent coronary angiography showed no stenotic lesions. The histological findings in endomyocardial biopsy showed thickened endocardium associated with significant eosinophilic infiltration, which was compatible with Löffler's endocarditis. After the administration of prednisolone, the patient's general condition, eosinophilia, ECG abnormalities, and histological findings were improved dramatically. The endomyocardial biopsy in the acute phase was helpful for diagnosis and therapeutic decision-making.
AuthorsHidetomo Maruyoshi, Satoshi Nakatani, Yoshio Yasumura, Akihisa Hanatani, Tomoyoshi Yamaguchi, Chikao Yutani, Hatsue Ishibashi-Ueda, Kunio Miyatake, Masakazu Yamagishi
JournalHeart and vessels (Heart Vessels) Vol. 18 Issue 1 Pg. 43-6 (Mar 2003) ISSN: 0910-8327 [Print] Japan
PMID12644881 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Glucocorticoids
  • Prednisolone
Topics
  • Aged
  • Echocardiography, Doppler, Color
  • Electrocardiography
  • Endocardium (pathology)
  • Glucocorticoids (therapeutic use)
  • Humans
  • Hypereosinophilic Syndrome (diagnosis, diagnostic imaging, drug therapy, pathology)
  • Male
  • Myocardial Infarction (diagnosis)
  • Prednisolone (therapeutic use)

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