Abstract | AIMS: The protective effects of natural honey against acetic acid-induced colitis were investigated in rats. METHODS: Honey and glucose, fructose, sucrose, maltose mixture were administered, orally and rectally, daily for a period of 4 days. Induction of colitis was done on the third day using 3% acetic acid. Animals were killed on day 4 two hours after administration of the dose and colonic biopsies were taken for macroscopic scoring, histopathological and biochemical studies. RESULTS: CONCLUSIONS: Further studies are required to explore the active ingredients responsible for the antioxidant effect of honey and its therapeutic potential in humans.
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Authors | A A Mahgoub, A H el-Medany, H H Hagar, D M Sabah |
Journal | Tropical gastroenterology : official journal of the Digestive Diseases Foundation
(Trop Gastroenterol)
2002 Apr-Jun
Vol. 23
Issue 2
Pg. 82-7
ISSN: 0250-636X [Print] India |
PMID | 12632976
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Acetic Acid
- Administration, Rectal
- Animals
- Colitis
(chemically induced, pathology, prevention & control)
- Colitis, Ulcerative
(prevention & control)
- Colon
(pathology)
- Honey
- Male
- Rats
- Rats, Wistar
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