[Antigen therapy in chronic brucellosis].

Abstract

The different forms of chronic brucellosis have been improved and well stabilized in the proportion of 75% by repeated injections of a vaccine consisting of suspensions of heat-killed B. melitensis. The vaccine should be used in a series of 8 subcutaneous injections, in increasing doses, at the rate of 2 injections a week. To obtain good results it is necessary to give an average of 3 to 4 series of injections, with a two months' interval between each series. After the 2nd series a distinct decrease of the patient's reactions to retarded hypersensitivity tests are generally observed. The most favourable results are obtained in cases of common subjective syndrome with physical and psychical asthenia.

• Authors: J Roux
• Journal: Developments in biological standardization (Dev Biol Stand) Vol. 31 Pg. 227-9 ( 1976) ISSN: 0301-5149 [Print] Switzerland
• Vernacular Title: L'antigénothérapie dans la brucellose chronique
• PMID: 1261738 (Publication Type: English Abstract, Journal Article)

Chemical References

• Antigens, Bacterial
• Brucella Vaccine

Topics

• Antigens, Bacterial (administration & dosage)
• Brucella (immunology)
• Brucella Vaccine (therapeutic use)
• Brucellosis (immunology, therapy)
• Chronic Disease
• Immunotherapy