Abstract | OBJECTIVE: METHODS: A total of 195 patients (106 males and 89 females) with lymphangiomas in oral and maxillofacial regions were treated in the affiliated dental hospital of Sichuan University from May 1990 to December 2000. The patients' ages ranged from 0.5 to 46 years. The tongue was the most commonly involved site, followed by the cheek and the neck. The 200 lymphangiomas (5 patients had 2 lymphangiomas in different sites) underwent the therapy of Pingyangmycin, which was injected as with 1 mg/ml in saline. The total dose of Pingyangmycin ranged from 5 mg to 70 mg and 5 to 58 times, 1 time per 2-4 weeks. RESULTS: The curative rate of cystic-type lymphangiomas was the highest. Of the 51 cystic lymphangiomas, 110 capillary lymphangiomas, 18 cavernous lymphangiomas and 21 combinations of capillary and cavenous lymphangiomas, the curative rates were respectively 100% (51), 46.36% (51), 16.16% (3) and 19.05% (4), which showed a significant therapeutic effect, respectively. And 40(78.43%), 19(17.27%), 2(11.11%) and 0(0%) of them completely disappeared. There was no serious side effect with Pingyangmycin-injection treatment, such as pulmonary fibrosis. CONCLUSION:
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Authors | Qinghong Gao, Changmei Wang, Yuming Wen |
Journal | Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology
(Hua Xi Kou Qiang Yi Xue Za Zhi)
Vol. 20
Issue 3
Pg. 184-6
(Jun 2002)
ISSN: 1000-1182 [Print] China |
PMID | 12600061
(Publication Type: English Abstract, Journal Article)
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Chemical References |
- Antibiotics, Antineoplastic
- Bleomycin
- zhengguangmycin
- Dexamethasone
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Topics |
- Adolescent
- Adult
- Antibiotics, Antineoplastic
(administration & dosage)
- Bleomycin
(administration & dosage, analogs & derivatives)
- Child
- Child, Preschool
- Dexamethasone
(administration & dosage)
- Drug Administration Schedule
- Female
- Head and Neck Neoplasms
(drug therapy)
- Humans
- Infant
- Injections, Intralesional
- Lymphangioma
(drug therapy)
- Male
- Mouth Neoplasms
(drug therapy)
- Tongue Neoplasms
(drug therapy)
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