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Copper metabolism in experimental Border disease.

Abstract
The proposal that hypocupraemia and hypocuprosis are characteristic manifestations of Border disease and of aetiological significance has been investigated. Mean plasma copper concentrations in 65 affected and 47 unaffected lambs were similar and in a controlled experiment, plasma and tissue copper concentrations tended to be higher in affected lambs than in controls. It is concluded that hypocupraemia and hypocuprosis are not consistent features of Border disease and thus have no aetiological significance.
AuthorsR M Barlow, N F Suttle, M B Derbyshire, A C Gardiner, J C Rennie
JournalThe Veterinary record (Vet Rec) Vol. 98 Issue 5 Pg. 86-8 (Jan 31 1976) ISSN: 0042-4900 [Print] England
PMID1258302 (Publication Type: Journal Article)
Chemical References
  • Copper
  • Ceruloplasmin
Topics
  • Animals
  • Brain (metabolism)
  • Ceruloplasmin (blood)
  • Copper (blood, metabolism)
  • Female
  • Liver (metabolism)
  • Male
  • Sheep
  • Sheep Diseases (metabolism)
  • Virus Diseases (metabolism, veterinary)

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