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Gabapentin for the treatment of tremor.

AbstractOBJECTIVE:
To review the use of the antiepileptic drug gabapentin for the treatment of various types of tremor.
DATA SOURCES:
A search of biomedical literature was completed through MEDLINE and EMBASE (1993-May 2002) to identify all clinical trials pertaining to the use of gabapentin for the treatment of tremor in humans.
DATA SYNTHESIS:
Outcome data from the few published studies have varied widely. Patient groups have been small, and conclusions have been based largely on subjective patient and investigator ratings.
CONCLUSIONS:
A trial of gabapentin is warranted in patients who fail therapy with traditional agents. Improvement should be measured by a patient's perceived functional ability.
AuthorsMichele A Faulkner, John M Bertoni, Thomas L Lenz
JournalThe Annals of pharmacotherapy (Ann Pharmacother) Vol. 37 Issue 2 Pg. 282-6 (Feb 2003) ISSN: 1060-0280 [Print] United States
PMID12549962 (Publication Type: Journal Article, Review)
Chemical References
  • Acetates
  • Amines
  • Cyclohexanecarboxylic Acids
  • gamma-Aminobutyric Acid
  • Gabapentin
Topics
  • Acetates (therapeutic use)
  • Adult
  • Aged
  • Amines
  • Clinical Trials as Topic
  • Cyclohexanecarboxylic Acids
  • Gabapentin
  • Humans
  • Middle Aged
  • Parkinson Disease (drug therapy)
  • Treatment Outcome
  • Tremor (classification, drug therapy, etiology)
  • gamma-Aminobutyric Acid

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