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Are antidepressants effective in fibromyalgia?

Abstract
Amitriptyline and other imipramine antidepressants are the cornerstone of drug therapy in fibromyalgia. However, some patients fail to respond to antidepressant therapy, and in responders the beneficial effects wear off after some time. The effect on fibromyalgia seems independent from the effects on depression.
AuthorsEric Thomas, Francis Blotman
JournalJoint bone spine (Joint Bone Spine) Vol. 69 Issue 6 Pg. 531-3 (Dec 2002) ISSN: 1297-319X [Print] France
PMID12537258 (Publication Type: Editorial, Meta-Analysis, Review)
Chemical References
  • Antidepressive Agents
Topics
  • Antidepressive Agents (adverse effects, therapeutic use)
  • Depression (complications, drug therapy)
  • Fibromyalgia (complications, drug therapy)
  • Humans
  • Treatment Outcome

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