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Urinary excretion of hydroxylysyl glycosides during acute inflammation in the rat.

Abstract
1. Subcutaneous inflammatory granuloma were induced in young rats and the urinary excretion of hydroxyproline and hydroxylysyl glycosides was observed during the period of acute inflammation. 2. All collagen metabolites were increased in the urine and excretion of glucosyl-galactosyl-hydroxylysine was much greater than excretion of galactosyl-hydroxylysine in the first days. 3. It is argued that urinary glucosyl-galactosyl-hydroxylysine is probably derived from hydroxylysyl residues of soluble collagen. 4. This study affords new arguments in favour of the dermal origin of urinary glucosyl-galactosyl-hydroxylysine, at least in skin inflammation.
AuthorsR Askenasi, M Le Lous, V H Rao, S Bazin
JournalClinical science and molecular medicine (Clin Sci Mol Med) Vol. 50 Issue 3 Pg. 195-7 (Mar 1976) ISSN: 0301-0538 [Print] England
PMID1253529 (Publication Type: Journal Article)
Chemical References
  • Galactosides
  • Glucosides
  • Hydroxylysine
  • Hydroxyproline
Topics
  • Acute Disease
  • Animals
  • Galactosides (urine)
  • Glucosides (urine)
  • Granuloma (urine)
  • Hydroxylysine (urine)
  • Hydroxyproline (urine)
  • Rats

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