[Treatment of hypercalcemia of malignancy with pamidronate in a patient with advanced recurrent oral cancer].

Abstract

Hypercalcemia of malignancy is a common problem for cancer clinicians. Treatment of hypercalcemia of malignancy with pamidronate in a patient with advanced recurrent oral cancer is reported herein. The patient was a 36-year-old man who had neck lymph node metastases due to recurrence of squamous cell carcinoma of the buccal mucosa and complained of cloudiness of consciousness due to hypercalcemia. The patient was administered pamidronate. A fine reduction in serum calcium was observed and cloudiness of consciousness was also alleviated. Although treatment of hypercalcemia with pamidronate is palliative, it is effective against the deterioration of quality of life.

• Authors: Norihiko Nishimura, Yuki Matsushita, Kazuki Takaoka, Susumu Hashitani, Kazuma Noguchi, Masahiro Urade
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 29 Issue 13 Pg. 2537-9 (Dec 2002) ISSN: 0385-0684 [Print] Japan
• PMID: 12506478 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antineoplastic Agents
• Diphosphonates
• Pamidronate

Topics

• Adult
• Antineoplastic Agents (therapeutic use)
• Carcinoma, Squamous Cell (drug therapy, pathology, secondary)
• Consciousness Disorders (etiology)
• Diphosphonates (therapeutic use)
• Drug Administration Schedule
• Humans
• Hypercalcemia (drug therapy, etiology)
• Lymphatic Metastasis
• Male
• Mouth Neoplasms (drug therapy, pathology, psychology)
• Pamidronate
• Quality of Life