Abstract | PURPOSE: DESIGN: Retrospective case series. METHODS: RESULTS: Nine of 11 eyes had subfoveal lesions while two eyes had juxtafoveal lesions on initial examination. Conversion from a choroidal neovascular membrane (CNVM) to a fibrous disciform lesion following photodynamic therapy was observed in nine eyes. Enlargement of the CNVM was noted in seven of these eyes by fluorescein angiography at final follow-up. Initial best-corrected visual acuity (BCVA) ranged from 20/25 to counting fingers (CF) (mean, 20/400; median, 20/200). Final BCVA ranged from 20/20 to CF (mean, 20/600; median, 20/400). Seven eyes with subfoveal CNVM had an initial BCVA of at least 20/200 while only three eyes maintained this level or better at last follow-up. In one patient with a juxtafoveal CNVM in one eye, vision decreased from 20/25 to 20/400 with enlargement and fibrosis of the CNVM and subfoveal extension. In the fellow eye a juxtafoveal CNVM was initially treated and then retreated earlier than TAP criteria at 6 weeks. Vision improved to 20/20 and has remained stable 5 months after the initial treatment. CONCLUSIONS:
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Authors | Saad Shaikh, Alan J Ruby, George A Williams |
Journal | American journal of ophthalmology
(Am J Ophthalmol)
Vol. 135
Issue 1
Pg. 1-6
(Jan 2003)
ISSN: 0002-9394 [Print] United States |
PMID | 12504689
(Publication Type: Journal Article)
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Chemical References |
- Photosensitizing Agents
- Porphyrins
- Verteporfin
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Topics |
- Adult
- Aged
- Angioid Streaks
(complications, drug therapy, physiopathology)
- Choroidal Neovascularization
(drug therapy, etiology, physiopathology)
- Female
- Fluorescein Angiography
- Humans
- Male
- Middle Aged
- Photochemotherapy
- Photosensitizing Agents
(therapeutic use)
- Porphyrins
(therapeutic use)
- Retrospective Studies
- Verteporfin
- Visual Acuity
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