Controlling the onset of natural cryptosporidiosis in calves with paromomycin sulphate.

Abstract

A prospective, controlled-blind field trial was conducted to evaluate the efficacy and safety of paromomycin sulphate, given for 10 days from birth, in preventing natural cryptosporidiosis in calves. In the untreated control group, oocyst shedding and diarrhoea followed the pattern that had occurred on the farm before the trial, consistent with a perinatal infection, whereas in the treated group, the prepatent period was significantly longer than in the control group (P < 0.01) and oocyst shedding and diarrhoea started only after the drug was withdrawn. However, the regimen did not reduce the incidence of disease in the treated group.

• Authors: A Grinberg, A Markovics, J Galindez, N Lopez-Villalobos, A Kosak, V M Tranquillo
• Journal: The Veterinary record (Vet Rec) Vol. 151 Issue 20 Pg. 606-8 (Nov 16 2002) ISSN: 0042-4900 [Print] England
• PMID: 12463536 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Chemical References

• Anti-Bacterial Agents
• Paromomycin

Topics

• Animals
• Anti-Bacterial Agents (therapeutic use)
• Cattle
• Cattle Diseases (parasitology, prevention & control)
• Cryptosporidiosis (prevention & control, veterinary)
• Cryptosporidium parvum (isolation & purification)
• Paromomycin (therapeutic use)
• Treatment Outcome