Improvement of acquired pendular nystagmus by gabapentin: case report.

Acquired Pendular Nystagmus (APN) may cause distressing visual symptoms in patients who are already suffering a severe general disease. Averbuch-Heller et al. conducted the first double-blind controlled study on treatment for APN. They showed that gabapentin substantially reduces pendular nystagmus and significantly increases visual acuity in the majority of patients. We present a patient with APN due to multiple sclerosis who suffered severe oscillopsy and reduction of visual acuity and who substantially benefited from a trial treatment with this agent.
AuthorsK Fabre, H Smet-Dieleman, T Zeyen
JournalBulletin de la Société belge d'ophtalmologie (Bull Soc Belge Ophtalmol) Issue 282 Pg. 43-6 ( 2001) ISSN: 0081-0746 [Print] Belgium
PMID12455139 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Acetates
  • Amines
  • Cyclohexanecarboxylic Acids
  • gamma-Aminobutyric Acid
  • gabapentin
  • Baclofen
  • Acetates (therapeutic use)
  • Administration, Oral
  • Amines
  • Baclofen (administration & dosage)
  • Cyclohexanecarboxylic Acids
  • Female
  • Humans
  • Middle Aged
  • Multiple Sclerosis (complications)
  • Nystagmus, Pathologic (drug therapy, etiology)
  • Treatment Outcome
  • gamma-Aminobutyric Acid

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