[Study of the real situation of improvement by Zopiclone in treatment of insomnia among persons working during night shifts].

Abstract

UNLABELLED:

We investigated the effect of adapted management of sleep on the duration and quality of sleep in shift workers working the night shift. Twenty-nine shift workers suffering from insomnia were included and treated with zopiclone (7.5mg/day) or placebo according to a random double-blind protocol. Patients completed a sleep diary and a wrist actigraph was used to evaluate episodes of rest/activity. A self-administered subjective sleep questionnaire was filled out just after awakening. Zopicone was found to increase the duration of sleep significantly (p<0.05) over the baseline duration after the first and second night on duty. Subjective estimation of sleep was better in patients taking zopiclone who exhibited a smaller number of shorter awakening episodes.

IN CONCLUSION:

zopiclone improves the quality and duration of sleep in shift workers suffering from insomnia.

• Authors: M A Quera-Salva, P Philip, J Taillard, R Letrequeser, H Allain, S Garcia-Acosta, I Kermad, J Krieger, M Dib
• Journal: Revue neurologique (Rev Neurol (Paris)) Vol. 158 Issue 11 Pg. 1102-6 (Nov 2002) ISSN: 0035-3787 [Print] France
• Vernacular Title: Etude en situation réelle de l'amélioration par la Zopiclone des insomnies chez les personnes travaillant en équipes de nuit.
• PMID: 12451343 (Publication Type: Clinical Trial, English Abstract, Journal Article, Randomized Controlled Trial)

Chemical References

• Azabicyclo Compounds
• Hypnotics and Sedatives
• Piperazines
• zopiclone

Topics

• Adult
• Azabicyclo Compounds
• Humans
• Hypnotics and Sedatives (therapeutic use)
• Male
• Middle Aged
• Occupational Diseases (drug therapy)
• Piperazines (therapeutic use)
• Sleep Disorders, Circadian Rhythm (drug therapy)
• Wakefulness