Abstract | PROBLEM: METHOD OF STUDY: Neonatal (C57BL/6J x A/J)F1 B6A female mice were injected from 3 to 6 days of age with sesame oil: ethanol (9:1; v:v), alone, or containing 20 microgg cortisone acetate, 20 microg E2, or 20 microg testosterone. Two additional groups were given 20 microg cortisone acetate in combination with 20 microg E2 or 20 microg testosterone. At adulthood the animals were killed, the stage of vaginal estrus determined, the ovaries examined for the presence of corpora lutea and follicular cysts, and circulating levels of progesterone, E2, and testosterone were measured by radioimmunoassay (RIA). RESULTS: CONCLUSION:
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Authors | John C Chapman, Soohong Min, Saichol Kunaporn, Keith Tung, Saureen Shah, Sandra D Michael |
Journal | American journal of reproductive immunology (New York, N.Y. : 1989)
(Am J Reprod Immunol)
Vol. 48
Issue 3
Pg. 184-9
(Sep 2002)
ISSN: 1046-7408 [Print] Denmark |
PMID | 12443030
(Publication Type: Journal Article)
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Chemical References |
- Testosterone
- Estradiol
- Cortisone
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Topics |
- Animals
- Anovulation
(chemically induced)
- Cortisone
(administration & dosage, adverse effects, analogs & derivatives)
- Estradiol
(administration & dosage)
- Female
- Immune System
(drug effects, physiology)
- Mice
- Mice, Inbred C57BL
- Ovarian Cysts
(chemically induced)
- Reproduction
(drug effects, immunology, physiology)
- Testosterone
(administration & dosage)
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