Breast cancer incidence and exposure to pesticides among women originating from Jaipur.

Abstract

Environmental contamination by pesticides has been documented in biotic and abiotic components. These persistent organic pollutants are lipid soluble, nonbiodegradable, and endocrine disrupters. The present study was therefore planned to determine whether the levels of these pesticides like DDT and its metabolites DDD and DDE, dieldrin, heptachlor, and HCH and its isomers (alpha, beta, and gamma) were higher in blood of breast cancer patients when compared with normal women who did not suffer from major diseases like blood pressure, tuberculosis, diabetes, thyroid dysfunction, arthritis, cancer, etc. and had not undergone any major surgery. The results indicated that organochlorine pesticides taken for analysis were found significantly high in breast cancer patients irrespective of age, diet, and geographic distribution.

• Authors: Vibha Mathur, Pradeep Bhatnagar, Raj Gobind Sharma, Veena Acharya, Rachana Sexana
• Journal: Environment international (Environ Int) Vol. 28 Issue 5 Pg. 331-6 (Nov 2002) ISSN: 0160-4120 [Print] Netherlands
• PMID: 12437282 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Insecticides
• Pesticides
• DDT

Topics

• Adult
• Age Factors
• Breast Neoplasms (epidemiology, etiology)
• Chromatography, Gas
• Chronic Disease
• DDT (adverse effects, blood)
• Diet
• Environmental Exposure
• Female
• Geography
• Humans
• Incidence
• India
• Insecticides (adverse effects, blood)
• Pesticides (adverse effects, blood)