[Inhibiting effect of intrathecal fentanyl on intraoperative vomiting during cesarean delivery under epidural anesthesia].

Abstract

OBJECTIVE:

To observe the inhibiting effect of intrathecal (IT) fentanyl on nausea and vomiting during cesarean delivery under epidural anesthesia.

METHODS:

Thirty healthy parturients (ASA grade I to II) were randomly assigned in equal numbers into control and fentanyl groups (n=15 each, patients in the latter group treated with IT fentanyl at the dose of 20 microgram/3ml). The incidence of nausea and vomiting during the elective cesarean delivery under epidural anesthesia between the 2 groups were compared and the neonates' Apgar scores assessed after the delivery.

RESULTS:

Intraoperative nausea and vomiting/retching were reduced in the IT fentanyl group as compared with the control group (6.7 % vs 33.3 % and 0 vs 26.7 %, P>0.05 and P<0.05 respectively). The neonates' Apgar scores were not significantly different between the 2 groups (P>0.05).

CONCLUSION:

IT fentanyl can decrease intraoperative vomiting during cesarean delivery performed under epidural anesthesia.

• Authors: Ming-Wen Ouyang, Miao-Ning Gu, Chun-Shui Lin
• Journal: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA (Di Yi Jun Yi Da Xue Xue Bao) Vol. 22 Issue 11 Pg. 1037-8 (Nov 2002) ISSN: 1000-2588 [Print] China
• PMID: 12433644 (Publication Type: Clinical Trial, English Abstract, Journal Article, Randomized Controlled Trial)

Chemical References

• Analgesics, Opioid
• Fentanyl

Topics

• Adult
• Analgesics, Opioid (therapeutic use)
• Anesthesia, Epidural (adverse effects)
• Cesarean Section (adverse effects)
• Female
• Fentanyl (therapeutic use)
• Humans
• Incidence
• Injections, Spinal
• Intraoperative Care
• Intraoperative Complications (drug therapy)
• Vomiting (drug therapy, epidemiology)