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The glitazones: a new treatment for type 2 diabetes mellitus.

Abstract
The glitazones are a new class of anti-diabetic drugs that act by improving sensitivity to insulin and are indicated in the treatment of type 2 diabetes. The glitazones have effects on carbohydrate and lipid metabolism and hold the promise of being able to influence the many components of the insulin resistance syndrome seen in type 2 diabetes. It is possible that the glitazones may be able to prevent or delay the cardiovascular disease which accompanies type 2 diabetes, long-term studies are required to determine if this is the case. In addition to drug treatment patients with type 2 diabetes should be strongly encouraged to make life style changes which will improve glycaemic control such as weight reduction and increase exercise.
AuthorsCaroline Bradley
JournalIntensive & critical care nursing (Intensive Crit Care Nurs) Vol. 18 Issue 3 Pg. 189-91 (Jun 2002) ISSN: 0964-3397 [Print] Netherlands
PMID12405274 (Publication Type: Journal Article, Review)
Chemical References
  • Dosage Forms
  • Hypoglycemic Agents
  • Thiazoles
  • Thiazolidinediones
  • Rosiglitazone
  • 2,4-thiazolidinedione
  • Pioglitazone
Topics
  • Diabetes Mellitus, Type 2 (drug therapy)
  • Dosage Forms
  • Drug Monitoring
  • Humans
  • Hypoglycemic Agents (therapeutic use)
  • Pioglitazone
  • Rosiglitazone
  • Thiazoles (therapeutic use)
  • Thiazolidinediones
  • United Kingdom

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