[Postoperative nausea and vomiting--pathophysiology, prophylaxis and treatment].

Abstract

Postoperative nausea and vomiting (PONV) are among the most common complications in operative medicine. Especially patients undergoing middle ear surgery or adenotonsillectomy are frequently associated with PONV (70 %). Furthermore, emesis carries the risk of severe postoperative complications and is associated with additional costs and distress in patient management. If the patient carries a high risk for postoperative emesis, the patient should receive a prophylactic antiemetic therapy. 5-HT 3 receptor antagonists are highly effective in prevention and management of PONV. This review will discuss pathophysiology, prophylaxis and treatment of postoperative nausea and vomiting after E.N.T. surgery.

• Authors: F Lipka, F Wappler, R Leuwer, J Schulte Am Esch
• Journal: Laryngo- rhino- otologie (Laryngorhinootologie) Vol. 81 Issue 10 Pg. 725-31 (Oct 2002) ISSN: 0935-8943 [Print] Germany
• Vernacular Title: Postoperative Ubelkeit und Erbrechen in der Hals-, Nasen- und Ohrenheilkunde. Pathophysiologie, Therapie und Prophylaxe-Eine Ubersicht.
• PMID: 12397523 (Publication Type: English Abstract, Journal Article, Review)

Chemical References

• Anesthetics
• Antiemetics
• Receptors, Serotonin
• Receptors, Serotonin, 5-HT3
• Serotonin Antagonists

Topics

• Anesthetics (adverse effects)
• Antiemetics (administration & dosage, adverse effects)
• Autonomic Nervous System (physiopathology)
• Humans
• Otorhinolaryngologic Diseases (surgery)
• Postoperative Nausea and Vomiting (physiopathology, prevention & control)
• Premedication
• Receptors, Serotonin (drug effects, physiology)
• Receptors, Serotonin, 5-HT3
• Risk Factors
• Serotonin Antagonists (administration & dosage, adverse effects)