Abstract | BACKGROUND: MATERIAL/METHODS: RESULTS: The adenosine deaminase level in tuberculous pleural effusions was higher than in non-tuberculous pleural effusions. The data we obtained suggest that the enzyme activity level could be a very reliable test in the differential diagnosis of tuberculous pleurisy in the Armenian population. The activity of isoenzymes ADA1 and ADA2, or their ratios to the total ADA activity, though valuable information, has no diagnostic advantage over total ADA activity in diagnosing this pathology. CONCLUSIONS: The results clearly point up the value of using a total ADA activity assay in Armenian clinics for the differential diagnosis of tuberculous pleurisy. Determinations of the activity level of the ADA1 and ADA2 isoenzymes provide no diagnostic advantage over total ADA activity.
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Authors | Nune A Andreasyan, Hripsime L Hairapetian, Yelizaveta G Sargisova, Sona S Mardanyan, Lena T Badalyan, Armen S Khanoyan |
Journal | Medical science monitor : international medical journal of experimental and clinical research
(Med Sci Monit)
Vol. 8
Issue 10
Pg. CR708-12
(Oct 2002)
ISSN: 1234-1010 [Print] United States |
PMID | 12388924
(Publication Type: Journal Article)
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Chemical References |
- Isoenzymes
- Adenosine Deaminase
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Topics |
- Adenosine Deaminase
(metabolism)
- Adolescent
- Adult
- Aged
- Body Fluids
(enzymology)
- Female
- Humans
- Isoenzymes
(metabolism)
- Male
- Middle Aged
- Pleural Effusion
- Retrospective Studies
- Statistics as Topic
- Tuberculosis, Pleural
(diagnosis, enzymology)
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