[Comparative DNA cytometric investigations on aneurysmal bone cysts and giant cell tumors].

Abstract

Giant cell-rich bone lesions consist of tumor-like lesions and true neoplastic giant cell tumors. In this study it was investigated whether DNA cytometry may contribute to the differential diagnosis between aneurysmal bone cysts and giant cell tumors. Statistically significant differences in the frequency of tetraploid stemlines were detected. Nevertheless, the knowledge of age, localization and radiological signs in addition to morphological findings are essential to distinguish between these lesions.

• Authors: M Werner, G Delling
• Journal: Der Pathologe (Pathologe) Vol. 23 Issue 5 Pg. 340-50 (Sep 2002) ISSN: 0172-8113 [Print] Germany
• Vernacular Title: Vergeleichende DNA-zytometrische Untersuchungen an aneurysmatischen Knochenzysten und Riesenzelltumoren.
• PMID: 12376859 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• DNA, Neoplasm
• DNA

Topics

• Adolescent
• Adult
• Aged
• Bone Cysts, Aneurysmal (genetics, pathology)
• Child
• Cytogenetics (methods)
• DNA (genetics, isolation & purification)
• DNA, Neoplasm (genetics, isolation & purification)
• Female
• Giant Cell Tumor of Bone (genetics, pathology)
• Humans
• Image Cytometry (methods)
• Karyotyping
• Male
• Middle Aged