Abstract |
A 15-month-old girl developed frequent seizures at the eruptive stage of exanthema subitum. The eruption persisted for 2 weeks. Serum immunoglobulin G antibody to human herpes virus type 6 (HHV-6) increased markedly. Interleukin-6 was elevated whereas HHV-6 deoxyribonucleic acid was not detected in cerebrospinal fluid. These findings suggest that immune-mediated reactions after HHV-6 infection rather than direct action of active HHV-6 are responsible for frequent seizures in this case.
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Authors | Tohshin Go, Kenji Nakamura |
Journal | European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society
(Eur J Paediatr Neurol)
Vol. 6
Issue 4
Pg. 221-3
( 2002)
ISSN: 1090-3798 [Print] England |
PMID | 12374589
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Antibodies, Viral
- Immunoglobulin M
- Interleukin-6
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Topics |
- Acute Disease
- Antibodies, Viral
(blood, immunology)
- Electroencephalography
- Exanthema Subitum
(blood, complications, immunology)
- Female
- Herpesvirus 6, Human
(immunology, metabolism)
- Humans
- Immunoglobulin M
(blood, immunology)
- Infant, Newborn
- Interleukin-6
(immunology)
- Periodicity
- Seizures
(complications, diagnosis)
- Severity of Illness Index
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