Retransplantation for recurrent hepatitis C.

Abstract

1. Primary orthotopic liver transplantation (OLT) for hepatitis C is performed with good results. 2. Re-OLT in hepatitis C virus (HCV)-infected transplant recipients is performed mostly for indications other than recurrent disease in the short-term after primary OLT. 3. Progressive allograft injury and loss caused by recurrent disease predict an increased need for re-OLT for HCV recurrence in the long term. 4. Outcomes of re-OLT for recurrent hepatitis C are equivalent to results for other indications of re-OLT. 5. Good outcomes are obtained in selected patients when re-OLT is performed early in the course of recurrent disease before transplant recipients become critically ill.

• Authors: Rafik M Ghobrial
• Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society (Liver Transpl) Vol. 8 Issue 10 Suppl 1 Pg. S38-43 (Oct 2002) ISSN: 1527-6465 [Print] United States
• PMID: 12362296 (Publication Type: Journal Article, Review)

Topics

• Graft Rejection (immunology)
• Hepatitis C (immunology, mortality, surgery)
• Humans
• Liver Cirrhosis (surgery, virology)
• Liver Transplantation (immunology)
• Recurrence
• Reoperation
• Survival Analysis
• Treatment Outcome