Pauci-immune extracapillary glomerulonephritis and atheromatous embolization.

Abstract

Renal atheroembolic disease presents several multisystemic signs and symptoms that may resemble the clinical signs of vasculitis. A few cases of renal atheroembolism associated with antineutrophil cytoplasmic antibodies (ANCA) have been described. We report the first case, to our knowledge, of a patient with cholesterol microemboli who also developed extracapillary glomerulonephritis in the presence of perinuclear ANCA (p-ANCA) with anti-myeloperoxidase ANCA. The patient had long-term follow-up of renal function after treatment with prednisone and cyclophosphamide.

• Authors: Beatriz Aviles, Isabel Ubeda, Julia Blanco, Alberto Barrientos
• Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation (Am J Kidney Dis) Vol. 40 Issue 4 Pg. 847-51 (Oct 2002) ISSN: 1523-6838 [Electronic] United States
• PMID: 12324923 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright 2002 by the National Kidney Foundation, Inc.

Chemical References

• Antibodies, Antineutrophil Cytoplasmic
• Autoantibodies
• Peroxidase

Topics

• Aged
• Antibodies, Antineutrophil Cytoplasmic (blood, metabolism)
• Arteriosclerosis (complications, drug therapy)
• Autoantibodies (blood, immunology)
• Diagnosis, Differential
• Embolism, Cholesterol (drug therapy, etiology)
• Glomerulonephritis (blood, diagnosis, drug therapy, immunology)
• Humans
• Kidney (blood supply, immunology)
• Male
• Peroxidase (immunology)
• Renal Artery Obstruction (drug therapy, etiology)