Abstract | BACKGROUND: DESIGN: We retrieved 10 cases with a primary diagnosis of craniopharyngioma and 5 cases with a diagnosis of Rathke cleft cyst for analysis. Five cases of normal pars intermedia of pituitary glands from autopsy served as controls. We evaluated the expression patterns of a broad range of low- to intermediate-molecular weight cytokeratins (CK7, CK8, CK10, CK17, CK18, CK19, and CK20) and high-molecular weight cytokeratins (K903: a combination of CK1, CK5, CK10, and CK14; and CK5/6) in these cases. RESULTS: CONCLUSION:
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Authors | Wei Xin, Mark A Rubin, Paul E McKeever |
Journal | Archives of pathology & laboratory medicine
(Arch Pathol Lab Med)
Vol. 126
Issue 10
Pg. 1174-8
(Oct 2002)
ISSN: 0003-9985 [Print] United States |
PMID | 12296753
(Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
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Chemical References |
- Biomarkers, Tumor
- Intermediate Filament Proteins
- KRT20 protein, human
- Keratin-20
- Keratins
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Topics |
- Adolescent
- Adult
- Aged
- Biomarkers, Tumor
(metabolism)
- Cell Count
- Central Nervous System Cysts
(metabolism, pathology)
- Child
- Child, Preschool
- Craniopharyngioma
(metabolism, pathology)
- Diagnosis, Differential
- Female
- Humans
- Immunohistochemistry
- Intermediate Filament Proteins
(metabolism)
- Keratin-20
- Keratins
(metabolism)
- Male
- Middle Aged
- Molecular Weight
- Pituitary Neoplasms
(metabolism, pathology)
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