[The populational structure of peripheral lymphocytes in patients in the acute phase of opisthorchiasis].

Abstract

The lymphocytic populations of the immune system were studied in patients diagnosed as having acute opisthorchiasis before and 1-3 days after treatment with biltricide in a dose of 60 mg/kg body weight. The acute phase of opisthorchiasis is characterized by the activation of B lymphocytes and immunological cellular reserve, by depressed T-lymphocytic population with a decreased helper inductor and suppressive killer potential. Three days after dehelminthization, there was a trend for immunoregulatory T cells to become normal. The high levels of B lymphocytes and zero cells were preserved.

• Authors: G A Kal'gina, T F Stepanova, A L Shonin
• Journal: Meditsinskaia parazitologiia i parazitarnye bolezni (Med Parazitol (Mosk)) 2002 Jan-Mar Issue 1 Pg. 16-8 ISSN: 0025-8326 [Print] Russia (Federation)
• Vernacular Title: Populiatsionnaia struktura perifericheskikh limfotsitov u bol'nykh v ostruiu fazu opistorkhoza.
• PMID: 12224257 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Anthelmintics
• Praziquantel

Topics

• Acute Disease
• Anthelmintics (therapeutic use)
• B-Lymphocyte Subsets (immunology)
• Humans
• Killer Cells, Natural (immunology)
• Lymphocyte Count
• Lymphocyte Subsets (immunology)
• Opisthorchiasis (blood, drug therapy, immunology)
• Praziquantel (therapeutic use)
• T-Lymphocyte Subsets (immunology)
• T-Lymphocytes, Helper-Inducer (immunology)
• T-Lymphocytes, Regulatory (immunology)
• Time Factors