[SAPHO syndrome: case report of an 18-year-old man and review of the literature].

Abstract

We report about an 18-year-old man, suffering from acne on his face and trunk and complaining about indefinite bone pains--without any trauma. SAPHO-syndrome was diagnosed which consists of synovitis, acne, pustulosis, hyperostosis and osteitis. Five types of this syndrome can be differentiated: spondarthritis hyperostotica pustulo-psoriatica, chronic recurrent multifocal osteomyelitis, inflammatory chest wall syndrome, isolated sternocostoclavicular hyperostosis, and the combined form of acne-associated spondarthritis and chronic recurrent osteomyelitis. Although the sapho-syndrome is very rare, it should be considered a possible diagnosis in the case of indefinite bone pains in combination with acne, pustulosis and hyperostosis.

• Authors: Gerald Wolf, Reingard Maria Aigner, Thomas Schwarz, Mark Peter Lorbach
• Journal: Wiener klinische Wochenschrift (Wien Klin Wochenschr) Vol. 114 Issue 8-9 Pg. 341-4 (May 15 2002) ISSN: 0043-5325 [Print] Austria
• Vernacular Title: Das SAPHO-Syndrom: Fallbericht eines 18-jährigen Mannes und Literaturübersicht.
• PMID: 12212370 (Publication Type: Case Reports, Journal Article)

Chemical References

• Technetium Tc 99m Medronate

Topics

• Acne Vulgaris (etiology)
• Acquired Hyperostosis Syndrome (diagnostic imaging)
• Adolescent
• Arthralgia (etiology)
• Clavicle (diagnostic imaging)
• Diagnosis, Differential
• Humans
• Male
• Radionuclide Imaging
• Sternum (diagnostic imaging)
• Technetium Tc 99m Medronate