Cerebral aspergillosis caused by Neosartorya hiratsukae, Brazil.

Abstract	We report the first case of infection by Neosartorya hiratsukae, an ascomycete in which the conidial state resembles Aspergillus fumigatus. The fungus caused a brain infection in a Brazilian woman, who died despite itraconazole treatment. Diagnosis was established by direct microscopic examination, computed tomographic scan, and magnetic resonance imaging of the brain, and repeated cultures from the lesions. The in vitro antifungal susceptibility of the isolate is provided.
Authors	Josep Guarro, Esper G Kallas, Patricio Godoy, Anna Karenina, Josepa Gené, Alberto Stchigel, Arnaldo Lopes Colombo
Journal	Emerging infectious diseases (Emerg Infect Dis) Vol. 8 Issue 9 Pg. 989-91 (Sep 2002) ISSN: 1080-6040 [Print] United States
PMID	12194781 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References	Antifungal Agents Itraconazole Amphotericin B
Topics	Aged Amphotericin B (therapeutic use) Antifungal Agents (therapeutic use) Aspergillosis Brazil Central Nervous System Infections (drug therapy, microbiology) Female Fungi (classification, isolation & purification, pathogenicity) Humans Itraconazole (therapeutic use) Mycoses (drug therapy, microbiology)

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