Abstract | OBJECTIVE: DATA SOURCES: STUDY SELECTION: Eleven studies were selected from 789 publications using published criteria. Incidence, risk and potential for prophylaxis were established through a structured review process. DATA EXTRACTION: After the structured review, a small number of studies were available for the consideration of incidence (2), natural history (4) and prophylactic therapy (2). DATA SYNTHESIS: CONCLUSIONS: Few of the multiple available studies concerning trauma, DVT and pulmonary embolism meet reasonable standards to establish clinical validity. Available guidelines for literature evaluation allow surgeons to select relevant articles for consideration. Patients with multiple trauma appear to be at significant risk for DVT. The death rate associated with subsequent pulmonary embolism is significant. There is reasonably good evidence to suggest that low molecular weight heparin will reduce this likelihood without a significant risk of treatment complications.
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Authors | Andrew B Hill, Brian Garber, Geoffrey Dervin, Andrew Howard |
Journal | Canadian journal of surgery. Journal canadien de chirurgie
(Can J Surg)
Vol. 45
Issue 4
Pg. 282-7
(Aug 2002)
ISSN: 0008-428X [Print] Canada |
PMID | 12174986
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Anticoagulants
- Heparin, Low-Molecular-Weight
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Topics |
- Adult
- Anticoagulants
(therapeutic use)
- Evidence-Based Medicine
- Heparin, Low-Molecular-Weight
(therapeutic use)
- Humans
- Incidence
- Male
- Multiple Trauma
(complications)
- Pulmonary Embolism
(epidemiology)
- Risk Assessment
- Venous Thrombosis
(epidemiology, prevention & control)
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