Abstract | BACKGROUND: METHODS: RESULTS: Women with partial hydatidiform moles had significantly higher serum levels of inhibin A (P < 0.001) and activin A (P < 0.001) than healthy pregnant women, several fold higher than the 95% confidence interval of control values. After evacuation, the levels of both inhibin A (P < 0.001) and activin A (P < 0.05) declined significantly to the levels of nonpregnant controls. Molar hCG concentrations were significantly higher than in normal pregnancy (P < 0.001), but some values within the 95% confidence interval of normal values. Despite a significant decrease (P < 0.05) after evacuation, hCG levels were still higher than in nonpregnant women. CONCLUSIONS:
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Authors | Pasquale Florio, Filiberto M Severi, Luigi Cobellis, Secondo Danero, Alice Bomè, Stefano Luisi, Felice Petraglia |
Journal | Cancer
(Cancer)
Vol. 94
Issue 10
Pg. 2618-22
(May 15 2002)
ISSN: 0008-543X [Print] United States |
PMID | 12173329
(Publication Type: Journal Article)
|
Chemical References |
- Biomarkers, Tumor
- Activins
- Inhibins
|
Topics |
- Activins
(blood)
- Adult
- Biomarkers, Tumor
(blood)
- Female
- Humans
- Hydatidiform Mole
(blood)
- Inhibins
(blood)
- Pregnancy
(blood)
- Uterine Neoplasms
(blood)
|