Abstract | OBJECTIVES:
Antibiotics are the mainstay for the treatment of men with bacterial prostatitis. Despite numerous treatment strategies involving various types, dosages and duration of antibiotics, no uniform standard has been widely adapted. Moreover, the economic burden of these therapies has been heretofore poorly described. The purpose of this study was to compare the cost effectiveness of various antibiotic treatment regimens for chronic bacterial prostatitis. METHODS: After reviewing the literature, we constructed a model that compared 90 days of double strength trimethoprim-sulfamethoxazole and 14, 28 and 60 days of ciprofloxacin 500 mg. Parameters examined included initial cure rates, relapse rates, total cure rates, pharmaceutical costs, and total cost of treatment. Using a spreadsheet Markov model, we applied cure rates and relapse rates to a hypothetical cohort of 100 men with culture positive chronic bacterial prostatitis. We then calculated cost of medications and total healthcare costs for the various drug regimens. RESULTS: CONCLUSIONS:
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Authors | Elie Kurzer, Steven Kaplan |
Journal | European urology
(Eur Urol)
Vol. 42
Issue 2
Pg. 163-6
(Aug 2002)
ISSN: 0302-2838 [Print] Switzerland |
PMID | 12160588
(Publication Type: Journal Article)
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Chemical References |
- Anti-Infective Agents
- Ciprofloxacin
- Trimethoprim, Sulfamethoxazole Drug Combination
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Topics |
- Anti-Infective Agents
(economics, therapeutic use)
- Bacterial Infections
(drug therapy)
- Chronic Disease
- Ciprofloxacin
(economics, therapeutic use)
- Cost-Benefit Analysis
- Drug Costs
- Health Care Costs
- Humans
- Male
- Markov Chains
- Models, Economic
- Prostatitis
(drug therapy)
- Trimethoprim, Sulfamethoxazole Drug Combination
(economics, therapeutic use)
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