The epidemiology of peripheral vein infusion thrombophlebitis: a critical review.

Abstract

We critically assessed studies on the clinical importance, diagnosis, incidence, and pathogenesis of peripheral vein infusion thrombophlebitis, including catheter-related and patient-related risk factors. We reviewed the evidence linking thrombosis, particularly prothrombotic states such as the inherited thrombophilic disorders, with peripheral vein infusion thrombophlebitis. Peripheral vein infusion thrombophlebitis occurs in 25% to 35% of hospitalized patients with peripheral intravenous catheters and has both patient-related implications (e.g., sepsis) and economic consequences (e.g., extra nursing time). Although duration of catheterization, catheter-related infection, and catheter material are important risk factors for peripheral vein infusion thrombophlebitis, patient-related risk factors are not well elucidated.

• Authors: Vicky Tagalakis, Susan R Kahn, Michael Libman, Mark Blostein
• Journal: The American journal of medicine (Am J Med) Vol. 113 Issue 2 Pg. 146-51 (Aug 01 2002) ISSN: 0002-9343 [Print] United States
• PMID: 12133753 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)

Topics

• Catheterization, Peripheral (adverse effects, methods)
• Female
• Humans
• Infusions, Intravenous (adverse effects)
• Male
• Prevalence
• Primary Prevention (methods)
• Prognosis
• Risk Factors
• Severity of Illness Index
• Thrombophlebitis (epidemiology, etiology)