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Choanal atresia: the result of maternal thyrotoxicosis or fetal carbimazole?

Abstract
We present the fourth published case of a child affected with choanal atresia following maternal treatment with carbimazole. The mother was receiving her highest dose of carbimazole at the crucial period for development of the choanae, between days 35 and 38.
AuthorsJulian Barwell, Grenville F Fox, Jonathan Round, Jonathan Berg
JournalAmerican journal of medical genetics (Am J Med Genet) Vol. 111 Issue 1 Pg. 55-6; discussion 54 (Jul 22 2002) ISSN: 0148-7299 [Print] United States
PMID12124735 (Publication Type: Case Reports, Journal Article, Review)
CopyrightCopyright 2002 Wiley-Liss, Inc.
Chemical References
  • Antithyroid Agents
  • Carbimazole
Topics
  • Adult
  • Antithyroid Agents (adverse effects)
  • Carbimazole (adverse effects)
  • Choanal Atresia (chemically induced, etiology)
  • Female
  • Fever (etiology)
  • Humans
  • Infant, Low Birth Weight
  • Infant, Newborn
  • Male
  • Microcephaly (chemically induced, etiology)
  • Pregnancy
  • Pregnancy Complications (drug therapy)
  • Thyrotoxicosis (drug therapy)

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