HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Acute myeloid leukemia and related conditions.

Abstract
Flow cytometry is the primary tool for phenotyping leukemias and related conditions. With the ever increasing numbers of antibodies commercially available, the ability to study and understand leukemias, myelodysplastic syndromes, and the myelodysplastic/myeloproliferative diseases is improving. Although the data generated by flow cytometry are not comprehensive enough to completely subtype leukemias or myelodysplastic syndromes into their myriad divisions, this wealth of information does provide phenotype, reproducible enumeration of blasts, certain prognostic information, and it can reveal the presence of cell populations with aberrant antigen profiles. An important drawback to flow cytometry as it is performed today is the inability to look at the cells that mark with the antibody panels used. As classifications of leukemia and related conditions evolve, flow cytometry continues to answer many of the questions asked and to provide critical information reliably and quickly.
AuthorsWilliam McClintock Todd
JournalHematology/oncology clinics of North America (Hematol Oncol Clin North Am) Vol. 16 Issue 2 Pg. 301-19 (Apr 2002) ISSN: 0889-8588 [Print] United States
PMID12094474 (Publication Type: Journal Article, Review)
Chemical References
  • Antigens, CD
  • Antigens, Neoplasm
  • Biomarkers, Tumor
  • Neoplasm Proteins
Topics
  • Acute Disease
  • Antigens, CD (analysis)
  • Antigens, Neoplasm (analysis)
  • Biomarkers, Tumor (analysis)
  • Cell Differentiation
  • Cell Lineage
  • Flow Cytometry (methods)
  • Humans
  • Leukemia, Myeloid (classification, diagnosis, pathology)
  • Myelodysplastic Syndromes (classification, diagnosis, pathology)
  • Myeloproliferative Disorders (classification, diagnosis, pathology)
  • Neoplasm Proteins (analysis)
  • Neoplasm, Residual
  • Neoplastic Stem Cells (chemistry, immunology)
  • Prognosis

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: